3D histopathology, made routine

Histopathology, the gold standard for cancer diagnosis, relies on 2D tissue slices, which can limit diagnostic accuracy and affect treatment decisions. Although volumetric analysis offers clear advantages, the field still depends on 2D methods.
Light-sheet fluorescence microscopy (LSFM) shows great potential for 3D imaging, but its adoption has been slowed by technical challenges.
The EIC-funded 3DPATH project will use advances in LSFM and data analysis, developed during the Human Brain Project, to build a clinical 3D tissue scanner, enabling more accurate diagnoses, better patient care, and positioning Europe at the forefront of next-generation diagnostics.